Sanguinary (Pseudochelerythrine) From Macleaya Cordata Extract

Product Name:Macleaya cordata Extract
Latin Name:Macleaya cordata (Willd.)
Part Used:Fruit
Active Ingredients:Sanguinarine chelerythrine protopine-Allocryptopine -

Allocrytopine Bocconine
Specification:15%   60% Sanguinarine(HPLC)
Description:

Macleaya cordata (Willd.)R.Br is a bloodroot which owns thousand year history

of medicinal usage in China. 13 kinds of alkaloids and other compounds such

as sanguinarine, toddaline, protopine, a-allocryptopine, bocconine, rhizoma

coptidis alkali, berberine, samin alkali and protopine are in the root and

aerial parts. Macleaya cordata  extract contains sanguinaine and

chelerythrine, which have fungicidal and insecticidal activity.

Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB

activation, IkappaBalpha phosphorylation, and degradation.

Macleaya cordata contains several alkaloids including sanguinarine,

chelerythrine, protopine, and allocryptopine.Our product, Macleaya cordata

extract mainly constains with sanguinarine and chelerythrine. It was been

show to be reversible inhibitors of the enzymatic hydrolysis of

acetylthiocholine.

It was reported that a study was made of a possible inhibitory action on the

enzymatic hydrolysis of acetylthiocholine by human erythrocyte

acetylcholinesterase of principal alkaloids isolated from Chelidonium majus

L. and Macleaya cordata and microcarpa,and of drugs Ukrain and

Sanguirythrine. Among all examined agents berberine, sanguinarine and

Sanguirythrine were the strongest inhibitors of this reaction.Judging from

the data obtained, sanguinarine and chelerythrine exert similar inhibitory

effects on the reaction of enzymatic hydrolysis of acetylthiocholine.

Application:
Feed antibiotics, Agriculture insecticide, Agriculture bactericide,

Veterinary injection