Sanguinaria canadensis L

Bloodroot is native to the moist woodlands of Eastern U.S. and Canada.  Bloodroot possess attributes that are remarkable and almost unbelievable.  Numerous doctors and researchers have investigated bloodroot the active chemical in bloodroot is 13methyl[1,3]benzodioxolo [5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium.
The sap of the plant is bright red and is especially abundant with the alkaloid sanguinarine which is derived from root system, bloodroot is known for its anti-cancer/anti-tumor, anti-inflammatory, anti-microbial (Sanguinarine broad in vitro activity against Gram-positive and Gram-negative bacteria, fungi, and some protozoa), anti-oxidant, and expectorant properties.

The effect of sanguinarine and its anti-proliferative and apoptosis nature was investigated and the following found to be true:

1. Bloodroot stops cancerous cells rapid growth. 

2. Bloodroot stops cancerous cells from abnormally increasing in number.  

3. Bloodroot stops the promotion of human epidermoid carcinoma cells, i.e., squamous cell (squamous cell is an invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body).

4. Bloodroot promotes the natural self-destruction (apoptosis) of cancer cells.

5. Bloodroot will not promote apoptosis at any strength or concentration to health, tissue.

6. Bloodroot will promote necrosis (cell death ) in healthy epidermal keratinocytes (keratinocytes are the predominant cell type in the epidermis and dermis i.e. skin tissue) in concentrations above -10 μM (10-6 per unit).